For Healthcare Professionals

For Healthcare Professionals

ArthriFon® - vibroacoustic therapeutic device

1. Fresh look on osteoartritis (OA) development.

2.Vibroacoustic (Sound) Technology
3. Benefits of ArthriFon®
4. Limitations of ArthriFon®

1. Fresh look on osteoartritis (OA) development.

The evolution of the osteoarthritis disease process is arbitrarily divided into three stages:

Stage I.

Proteolytic breakdown of cartilage matrix.

Stage II.

Fibrillation and erosion of cartilage surface with release of matrix molecule breakdown products into the synovial fluid.

Stage III.

The phagocytosis of cartilage matrix breakdown products and other materials by synovial macrophages induces a chronic inflammatory reaction in synovium, thereby producing local synthesis of proteases, proinflammatory cytokines, and catabolic factors.

The factors released by the synovium diffuse by synovial fluid and into the cartilage and induce additional cartilage breakdown by direct macromolecule proteolyses and stimulation of chondrocytes to increase the synthesis of proteases.

At this stage, the chondrocytes are hypersensitive to cytokine stimulation because of an increased level of cytokine receptors on cell membrane.

References : http: //gateway.ut.ovid.com; Rheumatology text book.

2. Vibroacoustic (vibrasound) Technology

Vibroacoustic therapy is a new sound technology that uses audible sound vibrations to alleviate pain and stress.

This technology is developed based on the recognition that external vibrations can influence body functions. A number of researchers have demonstrated the effectiveness of vibroacoustic therapy.

The term vibroacoustics comes from the Latin verb vibrare (to vibrate, wave) and the Greek verb akouein (to hear); vibroacoustic therapy involves sound that is "heard" through the body and it can be used as a medical solution. Vibroacoustic therapy devices use transducers (called vibraphones) to transmit vibrations in sound frequencies, directly to the body.

"Vibroacoustic therapy uses frequencies that fall within the range of human hearing. Low frequency ranges are most strongly felt and may contribute to a greater experience of pain relief." (Source: Vibroacoustic Sound Therapy Improves Pain Management and More; May/June2004 Holistic Nursing Practice Volume 18 Number 3 Pages 111-118.).

"Vibroacoustic stimulation possesses several qualities which make it a good choice for treatment of chronic musculoskeletal pain. Vibratory (vibroacoustic) stimulation has been found to more effective than placebo in the alleviation of chronic pain syndromes." (Source: 87; Scand J Rehabil Med.19 19(4): 153-8.).

" Vibratory (Vibroacoustic) stimulation was found to be just as effective or, in some patients, to be even more effective in reducing chronic musculoskeletal or orofacial pain." (Source: Acta Physiol Scand Suppl.1983: 523: 1-51.).

"Vibratory stimilation (used separately) in patients suffering from myofascial or musculoskeletal pain was found to be just as efficient and, in some patients, even more efficient as a pain suppressive solution, when compared to aspirin." (Source: Brain Res 1984 Mar 5:294(2): 201-9.).

ArthriFon® uses mechanical microvibrations in sound wave frequency, ranging from 3Hz to 1,500 Hz.

Two major effects of the vibratory (vibroacoustic) stimulation on the treated areas

1. Improvement in blood and lymph flow in treated areas.

ArthriFon® emits micro vibrations that mimic the vasomotor contractility of the capillary bed. By restoring capillary ability to move blood and lymph, ArthriFon®, frequencies from 1200 Hz to 400Hz, removes molecules from a synovium breakdown of cartilage matrix, which removes cause of pain.

In addition to this benefit is coupled the removal of toxins and inflammatory byproducts that lead to tissue damage. Thus, physiological stimulation of the circulatory system, regardless of the end organ (granting it must satisfy the range of penetration), will promote a natural healing process in the desired region.

ArthriFon® increases blood and lymph circulation by approximately 400 to 1500 percent. Sonar microvibrations make muscles expand and contract to help move blood and lymph via the capillary bed to the synovial bag around the joints. This feature increases production of synovial fluid and, as result, regenerates cartilage in the joints.

2. Suppress pain.

With frequencies ranging from 3 Hz to 100Hz, ArthriFon® decreases the ability of neurotransmitters to transmit pain signals to the brain by increasing internal losses in the transition path. The activation level of sodium channels (in myelinated neurotransmitters) remain the same, but the amplitude of pain pulses or signals delivered to the next sodium channel were reduced below threshold. Subsequent sodium channels in myelinated neurotransmitter will be not fired, because the amplitude of delivered pain pulses below sodium channel firing threshold. At this point, pain signals are stopped.

"Chesky theorized that a benefit of vibroacoustic music might result from stimulation of the Pacinian corpuscles, large mechanoreceptors located in the subcutaneous and connective tissues surrounding visceral organs and joints. These bulb-like structures surrounding nerve endings are sensitive to pressure."

"Chesky and co researchers Michel and Kondraske contend that the Pacinian corpuscle can react to stimulation by vibroacoustic technology in the 60 to 600 Hz range, known to affect these mechanoreceptors. When stimulated, the Pacinian corpuscle sends neurological nonpain messages to the brain that appear to inhibit the pain impulse." Other researchers have documented the effects of stimulation of Pacinian corpuscles at these frequencies."

(Source: Quillian TA, Sato M. The distribution of myelin and nerve fibers from Pacinian corpuscles. J Physiol. 1955; 129:167–176. Hubbard SJ. A study of rapid mechanical events in a mechanoreceptor. J Physiol. 1958; 141:198–218.)

For more information about ArthriFon® limited study, click here Clinical Trial Table

3. Benefits of ArthriFon®

Suppressed pain (increasing resistance of myelinated neurotransmitters, so a pain signal does not reach the brain).
Move more blood to the joint (delivery nutrition, oxygen).
Remove cartilage byproducts (toxins) from joint (cause of pain).
Increase production of synovial fluid (joint lubrication).
Opens capillaries, which increase blood flow to the joint.
Constantly changes applying frequencies will not allow body adapt to it.

ArthriFon® does not cause any side effects when used as indicated.

ArthriFon® increases blood and lymph flow in treated areas of the body.

4. Limitations of ArthriFon®

ArthriFon® emits microvibrations in the specific areas of application, covering approximately 2-3 inches in diameter and depth.

We do not recommend using ArthriFon®:

1. If you are pregnant.
2. In area with blood clots.
3. If patient has an acute infectious disease.
4. If patient has a cancer.
5. If patient has a fever.
6. In areas where there is an implanted defibrillator or pacemaker.
7. Longer than 1 hour at the time on the same joint.
8. On the head.
9. On the kidneys.
10. Directly or close to the heart.
11. On your pets.

Mikhail N. Lyubich MD, Board Certified,

Vice President Medical Research.

If you have questions, you can call Dr. Lyubich who is here for you to answer all your questions every Tuesdays and Thursdays from 4-7p.m EST:

1-877-283-2530

Order ArthriFon® here online at:

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